Serrapeptase

Information and Research about Serrapeptase

You should consult your Doctor if you are taking any medication.

The natural Chelation-Anti-Inflammatory Serrapeptase has had wide clinical use - spanning over twenty-five years
throughout Europe and Asia - as a viable alternative to salicylates, ibuprofen and the more potent NSAIDs. Unlike these
drugs, Serrapeptase is a naturally occurring, physiological agent with no inhibitory effects on prostaglandins and is devoid
of gastrointestinal side effects.
Uses:
1. Cardiovascular Disease
2. Arthritis
3. Rheumatoid Arthritis
4. Lung Problems
5. Eye Problems
6. Runny Nose and sinusitis problems
7. Sports Injuries
8. Inflammation of any kind
Serrapeptase is a proteolytic enzyme isolated from the micro-organism Serratia E15. This enzyme is naturally processed
commercially today through fermentation and was discovered in the silkworm intestine. This immunologically active
enzyme is completely bound to the alpha 2 macroglobulin in biological fluids. Histological studies reveal powerful anti-
inflammatory effects of this naturally occurring enzyme.
Serrapeptase digests non-living tissue, blood clots, cysts, and arterial plaque and inflammation in all forms. The late
German physician, Dr. Hans Nieper, used Serrapeptase to treat arterial blockage in his coronary patients. Serrapeptase
protects against stroke and is reportedly more effective and quicker than EDTA Chelation treatments in removing arterial
plaque. He also reports that Serrapeptase dissolves blood clots and causes varicose veins to shrink or diminish. Dr.
Nieper told of a woman scheduled for hand amputation and a man scheduled for bypass surgery who both recovered
quickly without surgery after treatment with Serrapeptase.

Serrapeptase - Technical Information and Studies

Serrapeptase (Serrapeptase) has wide clinical use spanning over twenty-five years throughout Europe and Asia as a
viable alternative to salicylates, ibuprofen and the more potent NSAIDs. Unlike these drugs, Serrapeptase is a naturally
occurring, physiologic agent with no inhibitory effects on prostaglandins and is devoid of gastrointestinal side effects.
Serrapeptase is a proteolytic enzyme isolated from the micro-organism, Serratia E15. This enzyme is naturally present in
the silkworm intestine and is processed commercially today through fermentation. This immunologically active enzyme is
completely bound to the alpha 2 macroglobulin in biological fluids. Histologic studies reveal powerful anti-inflammatory
effects of this naturally occurring enzyme.
Serrapeptase digests non-living tissue, blood clots, cysts, and arterial plaque and inflammation in all forms. The late
German physician Dr. Hans Nieper used Serrapeptase to treat arterial blockage in his coronary patients. Serrapeptase
protects against stroke and is more effective and quicker than EDTA Chelation treatments in removing arterial plaque. He
also reports that Serrapeptase dissolves blood clots and causes varicose veins to shrink
or diminish. Dr. Nieper told of a woman scheduled for hand amputation and a man scheduled for bypass surgery who both
recovered quickly without surgery after treatment with Serrapeptase.

A Potent Proteolytic Enzyme

The inflammatory response is an important mechanism for protecting the body from attack by invading organisms and
faulty cells. In the case of immune dis-regulation, the body loses its ability to differentiate between innocuous and
potentially dangerous substances. This defective mechanisms results in a wide array of autoimmune diseases such as
allergies, psoriasis, rheumatoid arthritis, ulcerative colitis, uveitis, multiple sclerosis and some forms of cancer.
Standard drug therapy for inflammatory-mediated diseases and trauma include steroids and non-steroidal anti-
inflammatory agents (NSAIDs). Both classes of drugs offer temporary, symptomatic relief from swelling, inflammation and
accompanying pain without treating the underlying condition. These drugs may also be immunosuppressive and cause
dangerous side effects. The conscientious physician must weigh the benefits and long-term risks associated with the use
of NSAIDs, especially in cases of rheumatoid arthritis. If left untreated, the inflammatory process itself can lead to limitation
of joint function and destruction of bone, cartilage and articular structures.
NSAIDs are among the most widely prescribed drugs for rheumatoid arthritis and other inflammatory joint conditions. Their
effects are mediated through inhibition of the biosynthesis of prostaglandins. They work by irreversibly blocking
cyclooxygenase, the enzyme which catalyses the reactions of arachidonic acid to endoperoxide compounds. The
neurological and gastrointestinal side effects of these agents have been reviewed in considerable detail. All of the
NSAIDs, with the exception of Cytotec, inhibit prostaglandin El, a local hormone responsible for gastric mucosai
cytoprotection. A common side effect from these medications is gastric ulcers. More serious adverse reactions such as
blood dyscrasias, kidney damage and cardiovascular effects have been noted. Most physicians rotate among the ten most
widely prescribed NSAIDs, as soon as one causes side effects or stops working.
The search for a physiologic agent that offers anti-inflammatory properties without causing side effects may have ended
with the discovery of the Serratia peptidase (SP) enzyme. This anti-inflammatory agent is in wide clinical use throughout
Europe and Asia as a viable alternative to salicylates, ibuprofen (sold as an OTC in the U.S.) and the more potent
NSAIDs. Unlike these drugs, SP is a naturally occurring, physiologic agent with no inhibitory effects on prostaglandins and
devoid of gastrointestinal side effects.

SP is an anti-inflammatory, proteolytic enzyme isolated from the microorganism, Serratia El5. This enzyme is naturally
present in the silkworm intestine and is processed commercially today through fermentation. This immunologically active
enzyme is completely bound to the alpha 2 macroglobulin in biological fluids. Histologic studies reveal powerful anti-
inflammatory effects of this naturally occurring enzyme.
The silkworm has a symbiotic relationship with the Serratia microorganisms in its intestines. The enzymes secreted by the
bacteria in silkworm intestines have a specific affinity to avital tissue and have no detrimental effect on the host’s living
cells. By dissolving a small hole in the ~ silkworm’s protective cocoon (avital tissue), the winged creature is able to
emerge and fly away. The discovery of this unique biological phenomenon led researchers to study clinical applications of
the SP enzyme in man.

In addition to its widespread use in arthritis, fibrocystic breast disease and carpal tunnel syndrome, researchers in
Germany have used SP for atherosclerosis. SP helps to digest atherosclerotic plaque without harming the healthy cells
lining Z the arterial wall. Today, researchers consider atherosclerosis an inflammatory condition similar to other
degenerative diseases. Some immunologists are even categorizing atherosclerosis as a benign tumour. Hardening and
narrowing of the arterial wall is a cumulative result of microscopic trauma; inflammation occurs in the presence of oxidized
lipids.
SP doesn’t interfere with the synthesis of cholesterol in the body, but helps clear avital tissue from the arterial wall. It is
important to note that cholesterol in its pure state is an antioxidant and a necessary component of the major organ
systems in the body. The use of medications, which block cholesterol biosynthesis, may eventually damage the liver and
compromise anti-oxidant status of the eyes, lungs and other soft tissues.
While studies with Serrapeptase in the treatment of coronary artery disease are relatively new, a wealth of information
exists regarding its anti-inflammatory properties. SP has been used as an anti-inflammatory agent in the treatment of
chronic sinusitis, to improve the elimination of bronchopulmonary secretions, traumatic injury (e.g. sprains and torn
ligaments), post-operative inflammation and to facilitate the therapeutic effect of antibiotics in the treatment of infections. In
the urological field, SP has been used successfully for cystitis and epididymitis.

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